An elevated plus-maze in mixed reality for studying human anxiety-related behavior
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چکیده
منابع مشابه
Modulation of Anxiety-Like Behavior in Sildenafil Citrate-Treated Mice Placed in an Elevated Plus-Maze
Introduction: Sildenafil, a phosphodiesterase-5 (PDE5) inhibitor, may have various effects on the central nervous system via the nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) pathway. Preclinical studies have shown the controversial effect of sildenafil on anxiety-like behavior in animals. This study was undertaken to investigate the acute effect of sildenafil on anxiety-like behavior...
متن کاملmodulation of anxiety-like behavior in sildenafil citrate-treated mice placed in an elevated plus-maze
introduction: sildenafil, a phosphodiesterase-5 (pde5) inhibitor, may have various effects on the central nervous system via the nitric oxide (no)-cyclic guanosine monophosphate (cgmp) pathway. preclinical studies have shown the controversial effect of sildenafil on anxiety-like behavior in animals. this study was undertaken to investigate the acute effect of sildenafil on anxiety-like behavior...
متن کاملModulation of Anxiety-Like Behavior in Sildenafil Citrate-Treated Mice Placed in an Elevated Plus-Maze
smooth muscles, and therefore, improved erection (McCullough, 2002; Ulhayathas et al., 2007). Evidence shows that sildenafil inhibits cGMP degradation in the brain (Hotchkiss et al., 2005; Riazi et al., 2006) and affects the central nervous system (Ulhayathas et al., 2007). In the NO-cGMP pathway, sildenafil modulates cognition, memory, reward-related stimuli, pain perception, seizure attack, n...
متن کاملAn Assessment of Changes in Open-Field and Elevated Plus-Maze Behavior Following Heat Stress in Rats
This paper presents the effect of high environmental heat on behavior of the male Charles Foster rats. Eighty rats were divided into three groups, subjected to (i) acute heat stress (ii) chronic heat stress and (iii) handling control group. Animals were exposed to the hot environment in a biological oxygen demand incubator at 38 ± 1ºC (relative humidity 45-50%) for four hours of continuous sing...
متن کاملEffect of inhalation alcoholic extract of Peganum harmala on induction of Anxiety like behavior in Elevated Plus-Maze
Based on the extensive application of Peganum harmala (P.h) seeds in the Asian traditional medicine, we tried to investigate its possible anxiety effect. Method: The effect of P.h. extract inhalation was evaluated in adult male rats using elevated plus-maze apparatus. The humidity of prepared ethanol extract was 37%. Animals in different groups (n=6) received 2, 4, 6, 12 or 18 gr/ml doses of...
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ژورنال
عنوان ژورنال: BMC Biology
سال: 2017
ISSN: 1741-7007
DOI: 10.1186/s12915-017-0463-6